Світ медицини та біології, 2023, № 4 (86)

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Перегляд Світ медицини та біології, 2023, № 4 (86) за Ключові слова "benign prostatic hyperplasia"

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    Remodeling of the urinary bladder due to benign prostatic hyperplasia
    (Полтавський державний медичний університет, 2023) Sarychev, L. P.; Savchenko, R. B.; Starchenko, I. I.; Sarychev, Y. V.; Sukhomlin, S. A.; Suprunenko, S. M.; Pustovoit, G. L.; Саричев, Леонід Петрович; Савченко, Роман Борисович; Старченко, Іван Іванович; Саричев, Ярослав Володимирович; Сухомлин, Сергій Адольфович; Супруненко, Сергій Миколайович; Пустовойт, Ганна Леонідівна
    According to the current protocols, treatment tactics in patients with benign prostatic hyperplasia is based on the activity of lower urinary tract symptoms, urodynamic parameters, and post void residual urine. At the same time, morphological changes in the detrusor remain without attention. The article presents data of the research the features of urinary bladder remodeling in patients with benign prostatic hyperplasia due to a long-term infravesical obstruction. 70 patients with benign prostatic hyperplasia in the stage of compensation, subcompensation and decompensation of the bladder were examined. According to the indications, the patients underwent prostatectomy, a biopsy of the anterior wall of the urinary bladder was taken. The study of morphological changes allows distinguishing three stages of urinary bladder remodeling in patients with benign prostatic hyperplasia: compensation, subcompensation and decompensation. As a result of prolonged infravesical obstruction in patients with benign prostatic hyperplasia, reverse, then irreversible morphological changes in the detrusor occur with the formation of urinary bladder rigidity. Substantiation of indications for surgical treatment in patients with benign prostatic hyperplasia, taking into account the morphological changes in the urinary bladder, makes it possible to prevent urinary bladder decompensation and related complications. Key words: benign prostatic hyperplasia, morphology, urinary bladder, remodeling.