Quercetin reduces the transcriptional activity of NF-kB in stable coronary artery disease

dc.contributor.authorChekalina, N.
dc.contributor.authorBurmak, Y.
dc.contributor.authorPetrov, Ye.
dc.contributor.authorBorisova, Z.
dc.contributor.authorManusha, Y.
dc.contributor.authorKazakov, Yu.
dc.contributor.authorKaidashev, I. P.
dc.contributor.authorКайдашев, Ігор Петрович
dc.contributor.authorЧекаліна, Наталія Ігорівна
dc.contributor.authorБурмак, Юрій Григорович
dc.contributor.authorПетров, Євген Євгенович
dc.contributor.authorБорисова, Зінаїда Олексіївна
dc.contributor.authorМануша, Юлія Іванівна
dc.contributor.authorКазаков, Юрій Михайлович
dc.date.accessioned2018-05-08T08:18:22Z
dc.date.available2018-05-08T08:18:22Z
dc.date.issued2018
dc.description.abstractThe aim of this study was to determine the effect of quercetin on the indicators of chronic systemic inflammation (CSI) in stable coronary artery disease (CAD). Methods: This study included 85 patients with CAD, stable angina pectoris, functional class (FC) II, and heart failure (=F) 0-y. Each patient was prescribed beta-blockers, statins, and aspirin. In addition, a total of 30 patients, forming the study group received quercetin at a daily dose of 120 mg for two months, while the remaining 55 patients made up the control group. The levels of cytokines, such as tumor necrosis factor (TNF-a), interleukin-1b (IL-1b), and interleukin-10 (IL-10) in serum and the expression of the inhibitor of kappa B a (IkBa) gene in blood mononuclear cells, were determined.uk_UA
dc.identifier.citationQuercetin reduces the transcriptional activity of NF-kB in stable coronary artery disease [Electronic resource] / N. Chekalina, Yu. Burmak, Ye. Petrov [et al.] // Indian Heart Journal. – 2018. – V. 70, Issue 5. – P. 593–597. – URL: https://doi.org/10.1016/j.ihj.2018.04.006uk_UA
dc.identifier.issn0019-4832
dc.identifier.urihttps://repository.pdmu.edu.ua/handle/123456789/7875
dc.language.isoenuk_UA
dc.publisherHigher State Educational Establishment of Ukraine “Ukrainian Medical Stomatological Academy”, Str. Shevchenka, 23, 36000, Poltava, Ukraineuk_UA
dc.subjectCoronary artery diseaseuk_UA
dc.subjectQuercetinuk_UA
dc.subjectChronic systemic inflammationuk_UA
dc.subjectCytokinesuk_UA
dc.subjectNuclear factor of transcription kappa Buk_UA
dc.titleQuercetin reduces the transcriptional activity of NF-kB in stable coronary artery diseaseuk_UA
dc.typeArticleuk_UA

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