Morphological manifestations of side effects caused by the radiocontrast agent tomohexol in the form of type i hypersensitivity reaction in a patient with arteriosclerosis obliterans of the lower extremities (case report)

Abstract

Today radiocontrast agents are widely used for their ability to contrast and visualise the vascular bed in most human tissues and organs. The agents can be grouped according to their chemical structure into monomers and dimers, as well as ionic and non-ionic compounds. The active agent in Tomohexol 350 is iohexol – a non-ionic monomeric iodinated and water soluble radiocontrast agent. Hypersensitivity reactions are rare with the use of these type of compounds, however they can in some instances cause anaphylactic shock.